Pediatric malignancies are not only caused by acquired DNA changes. They are the aftereffect of DNA changes that happened during a child’s early life, in some cases even before birth. Each time a cell isolates into 2 new cells, it must duplicate its DNA. This procedure isn't faultless, and errors occurs in mutation, particularly when the cells are developing rapidly. This sort of acquired mutation in gene can occur at any time in life. Sometimes, lifestyle factors plays a major role to influence cancer risk in youths, but generally this takes numerous years to play a role in a child's cancer-causing tumours. Environmental factors, for example, radiation exposure, have been connected with a few kinds of cancer causing tumours in children. A few researches have proposed that some parental exposures (E.g. smoking) may build a kid's risks of specific cancer causing tumours, yet more researches are expected to investigate these conceivable connections. Up until this point, most cancer causing tumours in children have not been appeared to have natural causes.